Doonesbury by Garry Trudeau for September 14, 1971
Transcript:
Didi: You know, Michael, even after a whole year of college, you remain an enigma...As far as I can see, you still haven't been able to hit it off with any girl. That's really amazing if you stop to think about it. Well, I'll be seeing you. Mike: (Cruelty comes in all shapes and sizes.)